PPT-Genomic/Genetic Testing Germline v Somatic testing and the importance of Molecular Tumor

Ben Ho Park MD PhD Johns Hopkins University Financial Disclosures I have financial relationships with commercial entities that are relevant to the content of this presentation Royalties from Horizon Discovery LTD. Somatic Symptom Disorder. Somatic symptom disorder. → a disorder in which persons become excessively distressed, concerned and anxious about bodily symptoms they are experiencing. Somatization pattern. Molecular Pathology Director: Frederick Nolte, Ph.D.. Cytogenetics and Molecular Genetics Director: . Daynna. Wolff, Ph.D.. Medical Director: Cynthia Schandl, M.D., Ph.D.. Associate Director: Julie Woolworth Hirschhorn, Ph.D.. Jack K. . Okamuro. National Program Leader for Plant Biology, . Crop . Productoin. & Protection, USDA-ARS. ARS Administrator’s Council Meeting. December 5, 2012. Beltsville, MD. Challenge. Food Security & Sustainability. 2/24/16. Update Your Table of Contents!. Page 16 – Intro. To Genetics Guided Reading. Page 17 – Mendel, Somatic Cells, and Gametes. Organisms that reproduce . sexually . are made up of two different types of cells.. Rob Finch, MS, CGC. Certified Genetic Counselor. Medical Science Liaison. Myriad Genetic Laboratories. Somatic vs. Germline Mutation . Tumor Testing vs. Germline Testing . Tumor Biopsy . Blood Test . Dina Paltoo, Ph.D., M.P.H.. NIH Office of Science Policy. Laura Lyman Rodriguez, Ph.D.. National Human Genome Research Institute. October 4, 2017. Housekeeping. Participants must register to join the webinar. Dr Fiona McRonald 11. th. June 2019. NCRAS, Public Health England. National Disease Registration Service (NDRS). 2. NAACCR-IACR, Vancouver, 2019. National Cancer Registration and Analysis Service (NCRAS). Rachel Butler, Head of Bristol Genetics Laboratory. National delivery of 100,000 . Genomes . P. roject. A remarkable achievement. Genomic Laboratory Hubs. South West Genomic Laboratory Hub (SWGLH). Partnership . Laura Yarram-Smith. SWGLH Solid Tumour Laboratory Lead. 20/09/2019. Breast Cancer Genomics. Genomics in England and Genomic Lab Hub. Genomic Test Directory. Genomic Biomarkers in Breast Cancer. Future technologies . CancerGenetics@utsouthwestern.edu | 214 - 645 - 2563 Somatic and Germline Genetic Testing Somatic Testing Most cancer is the result of acquired, or somatic , mutations that occur in a cell. Cancers Laura Yarram-Smith . Solid Tumour Lead SWGLH. July 2023. https://www.nbt.nhs.uk/south-west-genomic-laboratory-hub. Part of a Genomic Medicine Service. Bristol Clinical Genetics . Peninsula Clinical Genetics. Psychosomatic Disorders. Prominent . physical or bodily symptoms . associated with significant impairment or distress. Actual physical illnesses may or may not be present. . . Somatic Symptom and Related Disorders. Dr. Breno Fragomeni. Assistant Professor. Animal Science - UConn. Where are the labels?. Introduction . Why genomic prediction?. Higher accuracy. Shorter generation interval . Higher genetic gain. Genetic gain per year. biology – lessons from dairy cattle breeding. Dairy Cattle. 9 million cows in US. Attempt to have a calf born every year. Replaced after 2 or 3 years of milking. Bred via AI. Bull semen collected several times/week. Diluted and frozen.