PPT-Histone modifications Eukaryotic DNA is not naked; chromatin, DNA plus

histones 50 Five major histones H2A H2B H3 H4 and H1 highly basic Arg and Lys gt25 Roger Kornberg in 1974 Chromatin is made up of repeating units called nucleosomes

dna histone structure chromatin histone dna chromatin structure histones transcription proteins core lysine h2a h2b nucleosome amino gene specific

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