into Tissues Chapter 3 CHEMOKINES AND CHEMOKINE RECEPTORS Biologic Actions of Chemokines Chemokines are essential for the recruitment of circulating leukocytes from blood vessels into extravascular ID: 915357
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Slide1
Leukocyte Circulation and Migration into Tissues
Chapter 3
Slide2Slide3Slide4Slide5Slide6CHEMOKINES AND CHEMOKINE RECEPTORS
Slide7Slide8Biologic Actions of ChemokinesChemokines are essential for the recruitment of circulating leukocytes from blood vessels into extravascular
Extravascular chemokines stimulate movement of leukocytes and their migration toward the
chemical gradient
of the secreted protein, a process called
chemokinesis
Chemokines are involved in the
development of lymphoid organs
, and they
regulate the traffic of lymphocytes
and other leukocytes through peripheral lymphoid
Chemokines are required for the
migration of dendritic cells
from sites of infection into draining lymph nodes
Slide9Slide10MIGRATION AND RECIRCULATION OF T LYMPHOCYTES
Slide11High Endothelial Venules (HEVs)
Slide12Migration of naive and effector T lymphocytes
Slide13Slide14