PPT-Hemoglobin and anemia

Hemoglobin Hemoglobin is the protein molecule in red blood cells that carries oxygen from the lungs to the bodys tissues and returns carbon dioxide from the tissues back to the lungs Hemoglobin Hemoglobin . b. d. g. a. a. Chromosome 16. Chromosome 11. 25%. 25%. a. a. b. d. g. 25%. 25%. 48%. 48%. 1.5%. 0.5%. 1.5%. 0.5%. Hemoglobin synthesis. a. a. a. a. a. a. b. g. d. b. d. g. HbA. HbF. HbA. 2. 98%. ~1%. Mohammad Asgar Khan, MD. Anemia. Learning Objectives:. Learn the pathophysiology of anemia in CKD.. Learn the diagnostic challenges of anemia in CKD.. Learn the therapeutic strategies and related controversies in the treatment of anemia in CKD.. Be able to classify the different types of anemia. Understand the signs and symptoms associated with anemia.. Being able to interpret lab abnormalities to diagnose different causes of anemia. . Introduction to Anemia. Be able to classify the different types of anemia. Understand the signs and symptoms associated with anemia.. Being able to interpret lab abnormalities to diagnose different causes of anemia. . Introduction to Anemia. Dr. : Ahmad Sh. Silmi. IUG-Faculty of Health Science. 2. Objectives. At The End Of This Lecture You Will Be Able To:. Define . anemia. Discuss the causes . & . clinical significance of different categories of anemia. a pathophysiological condition in which the body cannot meet its demands for oxygen. . M: . Hb. <13.5 . Hct. <41 . F. : . Hb. <12 . Hct. <36 . Erythrocyte Indices . Hgb. M: 14.0-18.0 . Definition of Anemia. Who here is anemic?. Newborn baby boy with hemoglobin 12.8 g/. dL. 2 month-old baby girl with . hgb. 9.5 g/. dL. 4 year-old girl with . hgb. 10.6 g/. dL. 16 . y.o. . boy with . .. Epidemiology.. Classification.. Review the terminology used to discuss anemia.. Evaluation:. .. . • Address clues in the history and exam that can direct the evaluation. . • Describe one approach to using lab tests to make the diagnosis. . OBJECTIVES. Describe the . structure . of hemoglobin molecule. Describe . synthesis . of hemoglobin in brief.. List the . functions. of hemoglobin.. Enlist . various types. of normal and abnormal hemoglobin’s.. globin. chains. Abnormalities in these proteins are referred to as . hemoglobinopathies. Two hemoglobin gene clusters are involved in the production of hemoglobin and are located at the end of the short arm of chromosomes 16 and 11, respectively. . ESSAM . AHMED. M.B.Ch.B. , F.I.B.M.S. Peadiatric. . Hemato. -Oncologist. Objectives. 1- to understand the definition of anemia and recognize its different types according to . their etiology. 2- to be able to approaches to patient with anemia (investigations and treatment. Swarnakshi. . Upadhyay. Assistant Professor. School of Pharmaceutical Sciences, CSJM University. DEFINITION. Anemia.  occurs when you have a decreased level of . hemoglobin. in your red blood cells (RBCs). . How to classify . anemias. on the basis. of etiology and RBC parameters:. 1.) Decreased production vs. RBC loss (increased destruction or bleeding). 2.) RBC Size:. Macrocytic . ,. microcytic , normocytic. 471. Objectives. Quantitative determination of hemoglobin in a blood sample.. . Hemoglobin structure. Hemoglobin (. Hb. ) is a . porphyrin. –iron (II) . protien. in RBCs that transport oxygen from the lungs to the rest of the body and carbon dioxide back to the lungs..