PPT-The Ashkenazi Genome Project

Shai Carmi Peer lab Columbia University and The Ashkenazi Genome Consortium TAGC Boston September 2013 Outline Ashkenazi Jewish AJ Genetics and TAGC Basic Variant Statistics Utility in AJ Medical . I would like to thank the Center for German Studies at the Hebrew University for supporting this research with a generous grant. This paper was approved for publication by Prof. Moshe Zimmermann, dire Jeroen. . Raes. , Jan O . Korbel. , Martin J . Lercher. , Christian von . Mering. and Peer Bork. Presented by Daehwan Kim. Outline. Genome size. Genome sizes of Archaea, Bacteria, and Eukaryotes. Factors affecting genome and genome sizes . The Plot. Deepak . Purushotham. Hamid Reza . Hassanzadeh. Haozheng. . Tian. Juliette . Zerick. Lavanya. . Rishishwar. Piyush. . Ranjan. Lu Wang. The Outline. The Need & The Requirement. The Options. (as told by Michael Lynch). Genome size and complexity varies across the tree of life. Lynch 2007. Some Big Questions. What is the relationship between genomic and organismal size/complexity?. Are genome size changes adaptive, or passively acquired?. Dan Gilchrist. National Human Genome Research Institute. October 18, 2016. The ENCODE Project. 3D Data Access Through the ENCODE Portal. The ENCODE Encyclopedia. Tools for Investigating Genetic Variants. The Time and Place of European Gene Flow into Ashkenazi Jews Shai Carmi The Hebrew University of Jerusalem 2016 Joint work with Itsik Pe’er , James Xue (Columbia University) Ashkenazi History: Known Applications of DNA Technology. Advances in gene manipulation have made many things possible. This section investigates 4 key areas where gene manipulations will affect our lives:. The Human Genome Project. Tim Graubert, MD. Division of Oncology, Stem Cell Biology Section. Washington University School of Medicine. Siteman Cancer Center. Genome Center at Washington University. Genome Center Leadership. Rick Wilson. Kesheng Wang, PhD. Department of Biostatistics and Epidemiology. College of Public Health. East Tennessee State University. 2. Outline. Introduction . Alcohol dependence (AD). Genetic study. . Subjects and Methods. Richard Gibbs and George Weinstock man Genome Sequencing Center ) genome was sequenced in a project (12). This was the third mammalian project complex collaboration led by the BCM-HGSC (BAC skims, w T – Its History and Advancements into New Research and Technology Jutta Marzillier , Ph.D Lehigh University Biological Sciences September 5 th , 2014 Objectives Techniques that enabled genome sequ INT. J. DIAB. DEV. COUNTRIES (2000), VOL. 20 147Proteinomics Attempts are on to identify the exact three -dimensional structures of nearly 10,000, biologically important, proteins. These are the logic (HGP) is an international scientific research . project. with the goal of determining the sequence of chemical base pairs which make up . human. DNA, and of identifying and mapping all of the genes of the . CSE291: Personal Genomics for . Bioinformaticians. 01/. 10/17. The personal genomics revolution. 23andMe. : >1 million customers . (. $200). Genographic. Project: . >800,000 customers ($150). Family Tree DNA: .