PPT-Novel signaling paradigm regulating TOLL-like receptors in innate immune

cells Samar Abdulkhalek and Myron R Szewczuk Dept Biomedical and Molecular Sciences Queens University Kingston K7L 3N6 Ontario Canada speaker A novel signaling paradigm for cell surface TLR4 and intracellular TLR7 and TLR9. non-AIDS Morbidity. Peter W. Hunt, MD. Associate Professor of Medicine. UCSF HIV/AIDS Division. A shift in focus…. T cell activation as a target for interventions in the pre-ART era. Monocyte activation and inflammation a target during treated HIV disease. to maintain water flow in gutters and downpipes. 2. The . problem. Raychem solution. Features and benefits. 3. Melted snow refreezes. . Heat from the sun and the building. . melt the snow on the roof which refreezes. Clarence Lam, . Sanket. Patel, . Tairan. Yang, Narthaanan Srimurugathasan. PHM142 Fall 2016. Instructor: Dr. Jeffrey Henderson. Outline. Introduction and components of innate immunity. Differentiation from blood cells and mechanisms of phagocytosis. E . Wolf decoy for geese (plenty in New England).. Why are these decoys efficient?. Geese do not have pictures to teach their young ones what animals to avoid…. … and so they must be born with images of predators engraved in their brain. All organisms have innate behaviors that are inherited from parents that develop independently from the environment. Innate behavior is inherited from an individual’s parents and is not modified by the individual and is generally not affected by the organism’s environment, including an organism’s experiences.. Control of the Cell Cycle. Intracellular signaling. Pathways initiated by ligand binding to receptors, usually plasma membrane proteins. Modulate cell growth, metabolism, death, differentiation, movement, and invasion. Kuby Immunology. , . 7e: Chapter 3. Essential Concepts – 1. A cellular signal is any event that instructs a cell to change its metabolic or proliferative state. Signals are usually generated by the binding of a ligand to a complementary cell-bound receptor. Chapter 4. Immunologic Drugs and Vaccines. Topics. Physiology of Acquired Immunity. Immunization. Interferon Therapy. Immunosuppression. Immunoglobulins, Antitoxins, and . Antivenoms. Herbal and Alternative Therapies. forthcoming . in . Australasian Journal of Philosophy. central goals. My aims in this talk:. uncover the underlying nature of biological sensory powers. outline an approach to the accuracy conditions of sensory states. Learning objectives. By the end of this session student will be able to. . Define innate immunity, acquired immunity. . To understand cells involved in . innate . and acquired . immunity. IMMUNITY. The Immune System. The immune system is a group of cells & soluble molecules, which interact & distinguish patterns in the body as “self” or “non-self,” in order to eliminate those that are “non-self.”. Abbas. University of California San Francisco. FOCiS. Lecture outline. Components of innate immunity. Recognition of microbes and dead cells . Toll Like Receptors. NOD . Like Receptors/. Inflammasome. Van Delden C, Iglewski BH. Cell-to-Cell Signaling and Pseudomonas aeruginosa Infections. Emerg Infect Dis. 1998;4(4):551-560. https://doi.org/10.3201/eid0404.980405. PowerPoint Image Slideshow. This work is licensed under a . Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. .. Communication. As with people, it is vital for individual cells to be able to interact with their environment. In order to properly respond to externals stimuli, cells have developed complex mechanisms of communication that can receive a message, transfer the information across the plasma membrane, and produce changes within the cell in response to the message. The ability of cells to communicate through chemical signals originated in single cells and was essential for the evolution of multicellular organisms. (credit: modification of work by Vincent and Bella Productions).