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CorrespondingauthorTel441904321325fax441904321383Emailaddressjd34yorkacukJCDumvilleContemporaryClinicalTrials2720061

*Correspondingauthor.Tel.:+441904321325;fax:+441904321383.E-mailaddress:jd34@york.ac.uk(J.C.Dumville).ContemporaryClinicalTrials27(2006)1

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