PPT-Pain, Inflammation, NSAIDs and Analgesics

BY DR KAUKAB AZIM 1 Learning Outcomes By the end of the lecture the student should be able to Define and discuss the pathobiology of pain pathways Explain the molecular mechanism of action common to all . Manpreet . & . Olivia . Outline. Pain Receptors . WHO Pain Ladder. Pain . Treatment . . -> Types of Analgesics. . - NSAIDs. . - Opioids. . What are the . 2 main . types of pain?. Neuropathic pain. Pharmacology. WHAT ARE AUTACOIDS?. produced . in one organ and are transported via the lymph system . All . occur (made) naturally in the body.. OCCUR NATURALLY IN THE BODY. Terms & Definitions. Autacoids - Examples:. Q. Define analgesics?. Analgesics are the drugs which relive or suppress the sensation of pain by acting on CNS but without producing any degree of loss of consciousness.. Q. Classify narcotic analgesics with example?. Evaluating the Risks and Benefits. Most Frequently Used OTC Analgesics. Reasons Why These Drugs Are Widely Used. What Limits the Use of OTC Drugs?. Adverse Effects of OTC Analgesics. Efficacy of Aspirin in Headache. Pharmacological Therapy for Acute Pain. . RICHARD D. . BLONDELL. , MD; MOHAMMADREZA AZADFARD, MD; and . ANGELA M. . . WISNIEWSKI. , PharmD . State University of New York at Buffalo School of Medicine and Biomedical Sciences, Buffalo, New York . # . PHL 322, Lab. . 3# . Introduction. - Pain:. an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. - Analgesics :. NURS 1950. Pharmacology. Nancy Pares, RN, MSN. Metro Community College. 1. Pain is:. Pain tolerance is:. 2. Obj. 1 Define pain and Pain tolerance. Objective 2: Identify the factors which affect the individual’s response to pain. What is an analgesic?. How do you feel pain?. What does “physical dependence” mean? . What does ‘tolerance’ mean in this context?. Analgesics – reduce pain. Mild analgesics. . Mild analgesics, such as . P. ain. Perception of Pain. Emotion. S. ocial . and environmental . context. S. ocio-cultural background. Beliefs. Attitudes. P. ersonal expectations. Physical perturbations. P. sychological . recognition . . . Kumari. . Anjana. Assistant Professor. Deptt. . of Veterinary Pharmacology & Toxicology. Bihar Veterinary College, Bihar Animal Sciences University, Patna. Opioid analgesics. Are the drugs that significantly relieve pain by acting in central nervous system or on peripheral mechanisms without affecting consciousness.. A. nti-. I. nflammatory . D. rug. S. Professor Sue . Smith. National Heart and Lung Institute. sue.smith@imperial.ac.uk. Major Clinical Uses. Relief of mild-to-moderate pain (Analgesic). Toothache, headache, backache . Dr. . Shakir. H. Mohammed . Al_Alwany. LEC 2,3,4. Hyperplasia & Physiologic . Hyperplasia. HYPERPLASIA . Increase . in the number of cells . results in increase in size of the . organ. Sara Horst MD MPH. Alan Moss MD . Extra-intestinal Manifestations. Prevalence and incidence depends on definition: 6-47%. Can appear before or after diagnosis. Rogler. G et al. Gastroenterology 2021. ANALGESICS. . Inflammation:. . it is a biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants.. . Inflammation may ends with either :. . Complete healing .