PPT-Hemophilia HEMOPHILIA Inherited deficiency of factor VIII (hemophilia A) or factor IX

Sexlinked inheritance almost all patients male Female carriers may have mild symptoms Most bleeding into joints muscles mucosal and CNS bleeding uncommon Severity inversely proportional to factor level. Morey A. Blinder, M.D.. Associate Professor of Medicine. and Pathology & Immunology. Objectives. Coagulation factor disorders and treatment. Disorders of platelets and platelet transfusion. Adjunctive drug therapy for bleeding. Traits. and. Learned Behaviors. 4.10 Science concepts. . The student knows that organisms undergo similar life processes and have structures that help them survive within their environment. The student is expected to: . THROMBOPHILIA. Defects in physiologic anticoagulant pathways. Increased production of procoagulant. Antithrombin deficiency. Protein C deficiency. Protein S deficiency. Factor V . Leiden. Prothrombin G20210A gene mutation. Eventually broke away from the church for the church’s denial of an annulment. . The Wives of Henry VIII. Catherine of Aragon. Sister-in-law of Henry. Married him when she was 23, he was 17. Married 20 years.. Write down Three reasons why you think Henry VIII had Six wives.. Learning Objective: . To learn why Henry VIII got married so often.. OFF WITH HER HEAD!. Write in your Books the title and date and underline with a ruler.. . One maternal uncle of the child died due to prolonged bleeding following a minor surgery.. . O/E, No petechiae/purpura.. Lt Knee joint swollen, tender. Hemophilia and Coagulation Disorders. . Factor VIII (FVIII) is produced mainly by the liver via intracellulartransport via chaperone proteins such as Bip and LMAN-1.Once secreted into the plasma circulatory system, it immediatelybinds with are thirteen clotting factors to as classical hemophilia. In hemophilia B, the missing clotting factor is factor IX. Hemophilia B is sometimesreferred to as Christmas disease. Q. How does a person perspectives . and . the Kenyan Situation. .. Dr. Festus . Njuguna. Moi. University/MTRH. INTRODUCTION. Genetic X-linked disorder. Haemophilia. A and B. Affects 1 per 10,000 deliveries. 30% of cases due to new mutations. Dr. shatha Sami alyasrri. Assistant professor . Bleeding disorders during pregnancy and . delivery. . A. Inherited . Vascular abnormalities. Platelet disorders. Coagulation disorders. B.Acquired. Thrombocytopenia. . Chelsea Marion, MD. 1,4. , Oluwaseun Odewole, MD, MPH. 2,4. , Sheila Goel, MD. 3,4. . 1. Dept. of Pediatrics, Morehouse School of Medicine, Atlanta, GA. . 2. Dept. of Family Medicine, Morehouse School of Medicine, Atlanta, GA. . Dr. S. Parthasarathy . MD., DA., DNB, MD (. Acu. ), . Dip. Diab.DCA, Dip. Software statistics . PhD (. physio. ). . Mahatma . gandhi. medical college and research institute, . puducherry. , India. Robin Reid, MD. Clinical Director, Mary M Gooley Hemophilia Center. Hematologist and Medical Oncologist, Rochester Regional Health. July . 2021. Outline. History of the Mary M Gooley Hemophilia Treatment Center. with Severe . Hemophilia. A. NEJM ARTICLE DATED 26/1/2023. PRESENTED BY: DR FIROSE MR (JR1). AIM AND OBJECTIVE. To determine the efficacy, safety, and pharmacokinetics of . efanesoctocog. . alfa. for routine prophylaxis, treatment of bleeding episodes, and perioperative management in previously treated adults and adolescents with severe hemophilia A..