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SOS ENaCPIP3 C3G P IP 3 3G P GAB1 Insuli PDK12 PKC Akt p70 PKC GA G p85 JAK NIK p PI3K Akt Tsc1 SOCS3 Shc NI K N GRB2 GRB 2 IRS1 Fyn GRB10 Ras cRaf MEK12 ERK PDE3B PKA SGK JNK SHP2 IRS1 PTEN

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