PDF-The effects of a serotonin 2C receptor agonist on endogenous and amp

antagonists increase striatal DA 2A antagonists attenuate amphetamineinduced DA elevation in the striatum HYPOTHESIS The effects of 5HT agonists will mirror those previously shown for 5HT ant. Contact us at: contact.omics@omicsonline.org. OMICS . International . through its Open Access Initiative is committed to make genuine and reliable contributions to the scientific community. OMICS International journals have over . Zak Fallows. pharmacology@mit.edu. 2013-11-23. ESP Splash (Saturday). These slides are available online, along with fun 5-minute quizzes and other materials:. http://. datb.mit.edu. /. Are You in the Right Room?. Antidepressants and . Anxiolytic. Agents. History. Prior to antidepressant agent discovery in the 1950s, electroconvulsive shock was administered as well as opiates to induce euphoria in patients with anxiety. The 1950s was known as the Golden decade for the psychopharmacology industry. Nathan Kline went further to show that it had a stimulatory effect on depressed patients. . Formulating a Dynamic . Hypothesis. Once the problem has been identified and . characterized . over an appropriate time, modeler must develop a theory called “. dynamic hypothesis. ” that accounts for the problematic behavior.. A Selective Overview. Carl Rosow, M.D., Ph.D.. Disclosures. Consultant – Salix Pharmaceuticals. Topics for Today. Pharmacodynamics. Receptors, potency, efficacy. Agonists, antagonists. The dose response curve. David Chen. 11307120002. What is serotonin?. Neurotransmitter(. 神经递质. ). Also called 5-hydrotrptamine(. 5-HT. )5-. 羟色胺. Synthesized from . tryptphan. How does this system work?. Fig. from . Anxiolytic. Agents. History. Prior to antidepressant agent discovery in the 1950s, electroconvulsive shock was administered as well as opiates to induce euphoria in patients with anxiety. The 1950s was known as the Golden decade for the psychopharmacology industry. Nathan Kline went further to show that it had a stimulatory effect on depressed patients. . Pain. . Pain. persists Pain persists. or increases or increases. 1. . Non. -. opioid. ± adjuvant. 2. Weak . opioid. ± non-. opioid. ± adjuvant. 3. Strong . opioid. Anna Maria Nardiello. 1,. *, Lucia Sessa. 1,2. , Jacopo Santoro. 1. and Stefano Piotto. 1,2. 1. . Department of Pharmacy, University of Salerno, . Fisciano. , 84084, Italy. 2. . Research. Centre for . Thomas Jefferson University. Class of 2016. Objectives. Identify symptoms of serotonin syndrome. Identify medications at risk to cause syndrome development. Identify possible differential diagnoses. Discuss appropriate syndrome treatment. Ketamine and PCP . – glutamate receptor antagonists. LSD . – serotonin receptor agonist. Alcohol. – GABA-A and . GABA-B receptor agonist (also NMDA receptor antagonist). MDMA. – increases activity of serotonin, dopamine and noradrenaline by enhancing their release and/or inhibiting reuptake. Objectives. Discuss the pharmacology of . catecholamines. Classify & describe adrenergic α-agonists including actions, therapeutic uses & adverse. reactions.. Classify & describe adrenergic β-agonists including actions, therapeutic uses & adverse. Graded Dose-response . Relationships:. Agonist drugs mimic the action of the original endogenous ligand for the receptor (for example, isoproterenol mimics norepinephrine on β1 receptors of the heart). . At the end . of this session. students should be able to:. Describe serotonin (. 5HT. ) receptors including serotonin & . antiserotonin. drugs. Explain important clinical applications of serotonin related drugs..