PPT-CENTROMERE It is the part of the chromosome where the kinetochore binds.

It is the part where the spindle fibers bind during metaphase and anaphase stage The centromere consists of CEN DNA consisting of 120 nucleotide pairs CENTROMERE It has three kinds of sequences. Mike Clark, M.D.. Mitosis . technically is the process that duplicates a cell’s nucleus. The process of mitosis is . conventionally divided into . four . phases:. Prophase. Metaphase. Anaphase. Telophase. The behavior of kinetochore fiber microtubules has been examined in PtK1 cells during anaphase of mitosis. Cells in kinetochores. ECENT experiments clearly demonstrate that spindle microtubules are By, Joshua Deal. Medical Practice. Teacher: Nurse. Problem: Morals versus Hospital law. V.S.. Personal Experience. Insurance Leads to More . D. ouble Binds. Escaping the Bind. The bacterial chromosome is a double-stranded, circular DNA molecule associated with a small amount of protein. Eukaryotic chromosomes have linear DNA molecules associated with a large amount of protein. Henry County Professional Learning High School Session II. Chromosomal Mutations. Deletion. – part of the chromosome is missing. Starts with breaks in the chromosome. Radiation, heat, viruses, chemicals, etc.. Week’s Number. Lecture. 1. Introduction of human chromosomes. 2. Linkage, crossing over . 3. Chromosome mapping. 4. Sex determination systems and sex-linked inheritance . 5. Pedigree Analysis . 6. Pedigree Analysis . Chromatin – the less tightly coiled DNA-protein complex. Centromere – the region of the chromosome that holds the two sister chromatids together during mitosis.. SEX CHROMOSOMES & AUTOSOMES. Sex chromosomes are chromosomes that determine the sex of an organism, and they may also carry genes for other characteristics. . Chromosomes. The . term chromosome was coined by W. . Waldeyer. in 1888. .. Their . structures . varies in . different organisms . like . they are circular in . bacteria. . but . linear in eukaryotic organisms, however there number remains constant for a species.. by. Mark S. Nardone. &. Roland M. Nardone, Ph.D.. Foundation for Advanced Education in the Sciences, Inc.. At the National Institutes of Health. Bethesda, MD. Karyotyping . Source: National Human Genome Research Institute. Typically occur during meiosis (gamete formation) but can also occur during mitosis. Can lead to cancer some cases. We will look at: Translocation, Deletion, Duplication and Inversion. Few harmful gene mutations are passed on to the next generation because the zygote usually dies. If it lives, the offspring may have birth defects.. Euploid. Have the . normal. chromosome number. Polyploid. A cell with . extra sets. of chromosomes. Ex: triploid (3n). Aneuploid. Cells missing a single chromosome or having an extra chromosome. Alterations in Chromosome Number. TE. Tandem repeat monomer. TE. Transposable element. Single copy DNA. Spindle microtubules pulling apart . chromatids. Metaphase chromosome. 147bp plus 5-70bp linker = 150-220bp. 100bp plus 55bp linker = 155bp. Lecture 4. Mitosis. Mitosis is a part of the . cell cycle process . by which chromosomes in a cell nucleus are . separated into two identical sets of chromosomes. , each in its own nucleus. . In general, . Chromosome 2A. Chromosome 2B. Chromosome 3A. Chromosome 3B. Chromosome 4A. Chromosome 4B. Chromosome 5A. Chromosome 5B. Chromosome 6A. Chromosome 6B. Chromosome 7A. Chromosome 7B. Chromosome 8A. Chromosome 8B.