PPT-Meta and bioinformatics analysis of SNP of proteasome genes as possible molecular markers

Daugavpils 2019 I Trapina Drmed Genomica and Bioinformatic Institute of Biology University of Latvia Multiple sclerosis Multiple sclerosis MS involves an immunemediated process in which an abnormal response of the bodys immune system is directed against the central nervous system CNS. Early genomic theory. Nejati-Javaremi. et al (. 1997. ) tested use of genomic relationship matrix in BLUP. Meuwissen et al (. 2001. ) tested linear and nonlinear estimation of . haplotype. effects. Toward Better Oats. Nick Tinker, 2014-March-5. Agriculture and Agri-Food Canada. . C. ollaborative . O. at . R. esearch . E. nterprise. * Mexico:. Julio Huerta. Eduardo Villa senior . Mir. Eduardo . Kun Huang. Department of Biomedical Informatics. OSUCCC Biomedical Informatics Shared Resource. The Ohio State University. 2011. Outline . Introduction. Genetic variations. Technologies. Array-based technology. analysis. SNP/genomic signature. Clinical sampling. Personalized chemotherapy. Personalized Targeted therapy. Personalized RNA therapy. Personalized radiation therapy. drugs. Targeted molecules. s. iRNA. Welcome to . PolyMarker. !. http://polymarker.tgac.ac.uk/. How to use Biomart to find SNP markers www.wheat-training.com. Options:. Design your own primers. Download pre-designed primers for SNP data. Richard H. Scheuermann, Ph.D.. Director of Informatics. JCVI. Outline. What is Bioinformatics? . Some definitions. Data types and analysis objectives. Big Data. T. he Big Data . value proposition. The Power of Bioinformatics. Dr. . Matthew . Cserhati (UNMC). Nebraska . Wesleyan. Phage Symposium. April 15, 2016. Personal introduction. MSc: . biology. , . Eotvos Lorand University, Hungary. BSc: . University of Szeged, . software engineering, Hungary. BMI/CS 776 . www.biostat.wisc.edu/bmi776/. Spring . 2018. Anthony Gitter. gitter@biostat.wisc.edu. These slides, excluding third-party material, are licensed under . CC BY-NC 4.0. by Mark . Craven, Colin Dewey, and Anthony Gitter. Daniel Kling & Andreas . Tillmar. daniel.kling@rmv.se. andreas.tillmar@rmv.se. Agenda . 10am-12pm. «Small» . (ForenSeq, ICMP panel. ). Markers. Typing technology. Statistical concepts of relevance. Lecture 1 – Introduction . to . Bioinformatics. Petrus Tang, Ph.D. (. 鄧致剛. ). Graduate Institute of Basic Medical Sciences. and. Bioinformatics Center, Chang Gung University. .. petang@mail.cgu.edu.tw. Kesheng Wang, PhD. Department of Biostatistics and Epidemiology. College of Public Health. East Tennessee State University. 2. Outline. Introduction . Alcohol dependence (AD). Genetic study. . Subjects and Methods. Outline. Introduction. Two review papers. Quality control (. MetaQC. ). Meta-analysis for detecting differentially expressed genes (. MetaDE. ). Meta-analysis for detecting pathways (. MetaPath. ). 1. Introduction. Inês Barroso. Joint Head of Human Genetics. Metabolic Disease Group Leader. Wellcome. Trust Sanger Institute. 1. Objectives. Why perform meta-analysis?. How? . What are the issues to consider?. What can you gain?. . BioMart. to extract SNP information. http://plants.ensembl.org/biomart/martview. How to use Biomart to find SNP markers www.wheat-training.com. How to use Biomart to find SNP markers www.wheat-training.com.